Generic Levitra at Online Canadian Pharmacy | Canadian Health&Care Mall
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Uses, Dosage, Side Effects Consumer Information, Action and Effects, How to take, interactions and Allergic Reactions, Precautions and Contraindications, Coupons, Where to Buy Online, Levitra vs Viagra and Cialis and The Expert Summary on Generic Levitra
- Levitra Uses
- What Does Generic Levitra Do?
- Levitra Dosage And Taking Instructions
- Who Can Use Generic Levitra
- Generic Levitra vs Other Drugs
- Levitra Side Effects
- Safe Generic Levitra in Online Canadian Pharmacy
- Levitra vs Viagra, Levitra vs Cialis
- Your Levitra Coupon Online
Levitra (Vardenafil) is an oral drug used for symptomatic treatment of erectile dysfunction (ED). Taken as directed by practitioner, approximately one hour before sexual activity. The drug will make it possible to restore erectile function for a brief period of time, during which the person affected by ED will be able to achieve several erections (as needed) and maintain them during as much time as it is seen opportune for a satisfactory sexual intercourse.
Levitra is used to temporarily restore erectile function. The drug will alleviate symptoms of erectile dysfunction for a limited period of time. During the time of Levitra efficiency man is able to achieve and maintain erection upon volition, when sexually aroused or stimulated. The drug will not work in the absence of adequate stimuli. Levitra does not affect libido, which means that the temperament and sexual stamina will remain habitual for the patient. Do not take Levitra recreationally with purpose of increasing sexual desire, since it has no qualities of an aphrodisiac.
What Does Generic Levitra Do?
Levitra’s main component is a chemical called vardenafil, which was discovered as a follow-up to the very first oral pill for ED, Viagra Generic. Vardenafil was approved for use in patients in 2003. The chemical is an inhibitor of a certain enzyme, phosphodiesterase type 5. This type of phosphodiesterase (PDE5) is responsible for termination of sexual act and constriction of blood vessels in the penis. Inhibiting of its action results in vasodilating process, which allows absorbing and retaining within as much blood as is needed for a hard and controllable erection to take place.
When a pill of Levitra starts producing its effect, it basically blocks the action of PDE5 and, when man is exposed to adequate sexual stimulation, the drug allows responding with erection that feels and looks completely natural. The action of Levitra extends up to 4-5 hours, a subject to fluctuation among individuals.
Levitra Dosage And Taking Instructions
Being a prescription drug, Levitra is taken as administered by healthcare provider. General guidelines instruct to take a tablet of Levitra by mouth at least 40-60 minutes before you plan to have a sexual activity, but not later than 3 hours before the stipulated time. The effects of vardenafil will continue for approximately 4 hours. During this time you will be able to respond to sexual stimulation with controllable and reliable erection. Recovery time normally improves, too, based on data collected from test groups. It is important not to crush the pills in your mouth or chew them before swallowing. Take the pill with a sufficient amount of water in order to facilitate its absorbing and peristalsis.
Levitra is available in doses 5, 10 and 20 mg. It is recommended not to exceed the dose of vardenafil 20 mg in order to avoid adverse events associated with overdose. Levitra can be taken with or without food. The onset of vardenafil action is delayed after simultaneous intake of food with high fat content.
Dose adjustment is not recommended for persons over 65 years of age. However, any increase of dose should be carried out with care and under constant supervision of prescriber. Do not skip checking in with your practitioner, keeping them informed about your response towards increase in the dose if you belong to the group of patients of 65 and above.
In patients with hepatic insufficiency mild to moderate degree (class A-B classification Child-Pugh) the initial recommended dose of Levitra is vardenafil 5 mg per day. Given the efficacy and tolerability of daily dose can be further increased. The maximum recommended dose for patients with hepatic impairment average degree (Class B classification Child-Pugh) which is Levitra 10 mg.
For patients with renal insufficiency mild to moderate severity there is no need for dose adjustment. For patients with severe renal impairment (creatinine clearance <30 mL / min) the recommended initial dose level of 5 mg. Given the efficacy and tolerability of further daily dose can be increased to 10 mg and 20 mg.
Vardenafil is not indicated for the use of persons under 18 years. There are no appropriate indications for the use of Levitra in children.
Who Can Use Generic Levitra
Levitra is generally well tolerated by patients of varied age groups. However, the use of vardenafil is not recommended in the following cases:
- Individual hypersensitivity to the active substance or to any of the ancillary components of the drug;
- concomitant use of vardenafil with nitrates or nitric oxide donors (such as amyl nitrite) in any form;
- patients with loss of vision in one eye because of non-arterial anterior ischemic optic neuropathy (NAION, know more about it on this page), regardless of whether it is the result of previous exposure inhibitor of phosphodiesterase type 5 (PDE-5).
Due to lack of information on the safety of vardenafil for the following patient groups and availability of a more detailed information about this drug is not administered patients with the following conditions:
- severe hepatic impairment (Class C classification Child-Pugh)
- renal disease in the terminal stage (with required hemodialysis)
- arterial hypotension (blood pressure less than 90/50 mm Hg)
- after suffering a stroke or myocardial infarction (within the last 6 months)
- unstable angina
- inherited retinal degenerative diseases (eg retinitis pigmentosa)
Generic Levitra vs Other Drugs
Concomitant use of vardenafil with potent inhibitors of CYP3A4 (ketoconazole and oral form of intrakonazol, learn more: https://en.wikipedia.org/wiki/CYP3A4) is contraindicated in men aged 75 years and above. Concomitant use of vardenafil with HIV protease inhibitors such as indinavir and ritonavir is contraindicated as they are potent inhibitors SYRZA4.
Typically, drugs for treatment of erectile dysfunction should not be applied to men for whom sexual activity is undesirable (eg patients with severe cardiovascular disease such as unstable angina or severe heart failure).
Before making a decision in favor of vardenafil administration, practitioner should collect full medical history and conducted a medical examination of the patient to diagnose erectile dysfunction and determine the underlying causes of the disease.
Before the treatment of erectile dysfunction doctor should check the status of cardiovascular patients because sexual activity is associated with some risk of complications of the cardiovascular system. Vardenafil has vasodilator properties which may result in minor transient reduction in blood pressure. Patients with obstruction of the left ventricular output department, for example, with stenosis and aortic stenosis, idiopathic hypertrophic subaortalnym may be sensitive to the action of vasodilators, including PDE5 inhibitors type.
Preparations for the treatment of erectile dysfunction (read about ED meds in this article: https://www.canadianhealthmall.com/the-way-thousands-of-people-buy-quality-ed-drugs-and-save-their-money-revealed.html) with extreme caution should be used in patients with anatomical deformation of the penis such as angulation, cavernous fibrosis or Peyronie’s disease, and patients with diseases that contribute to the development of priapism (serpopodibnoklitynna anemia, multiple myeloma or leukemia).
The safety and efficacy of Levitra coated tablets in combination with tablets, dispersible medications, Levitra ODT, or in combination with other drugs for the treatment of erectile dysfunction is unexplored, and hence such combinations is not recommended.
Vardenafil (get more information) is metabolized primarily liver enzyme cytochrome P450 isoforms ZA4 (CYP) and partly by CYP2S CYRZA5 isoforms. Therefore, inhibitors of these enzymes may reduce vardenafil clearance.
In a study involving 18 healthy male volunteers, there was no single enhance of hypotensive effect of nitroglycerin, which is used sublingually (0.4 mg) while taking vardenafil 10 mg at various time intervals (from 1 hour to 24 hours) to use doses of nitroglycerin .
In healthy volunteers of middle age hypotensive effect of nitrates, which were used sublingually (0.4 mg) in 1 and 4 hours after vardenafil, amplified the application vardenafil tablets coated with 20 mg. These effects were not observed when receiving a single dose of vardenafil tablets coated 20 mg to 1 day before the use of nitroglycerin.
Information on the potential hypotensive effects of vardenafil with concomitant use of nitrates is missing because their concomitant use is contraindicated. Nikorandyl a hybrid calcium channel activator and nitrate. Because of nitrate component it is able to engage in considerable interaction with vardenafil. Since a-blocker monotherapy can cause marked lowering of blood pressure, especially postural hypotension and swoon, were studies of drug interaction with vardenafil.
During these two studies involving healthy volunteers with normal blood pressure after forced titration of α-blockers with tamsulosin or terazosin at high doses with simultaneous use of vardenafil there were reported cases of hypotension (sometimes symptomatic) in a large number of persons. In patients treated with terazosin, hypotension was observed more frequently with concomitant use of vardenafil and terazosin than when the drugs are taken separately at an interval of 6 hours.
Levitra Side Effects
Side effects of Levitra are minimal, which makes the drug stand out among other medications belonging to the family of PDE5-inhibitors. The few side events patients report most commonly tend to disappear altogether as therapy continues and body adjusts to the effects of vardenafil. If this has not happened in your case, or if you find any adverse effects of Levitra particularly bothersome, you should consult your prescriber who will, in their turn, consider levelling up your dose according to your body tolerance threshold.
Most common side effects of Levitra are as follows:
- Upset stomach
- Stuffy, rheumy nose
- Fatigue, paraesthesia, dysaesthesia
- Sleep disorders
- Eye disorders, photophobia, compromised color perception, ocular pain or discomfort
- Back pain, muscle pain (myalgia), cramps
- Nasal bleeding
- Drop of blood pressure
- Increase of blood pressure
- Gastro-oesophageal reflux disease, gastritis, pain along the digestive tract and in the abdomen, diarrhea, vomiting, nausea, dry mouth
The following side effects, however, call for immediate medical attention and should be communicated to prescribe within the shortest period of time, with potential cancellation of vardenafil therapy:
- Allergic swelling and other severe allergic reactions
- Impaired breathing
- Increased heart rate
- Loss of consciousness, amnesia
- Pain in chest (angina), jaw or arm
- Sudden deafness
- Prolonged and / or painful erection, priapism
- Haematospermia, urethral bleeding
- Myocardial infarction, ventricular tachycardia, angina
Urethral bleeding and / or haematospermia that were associated with the use of all PDE5 inhibitors, including vardenafil, there have been no reported cases in clinical trials and in spontaneous postmarketing reports during the period of observation.
During the use of Levitra 20 mg coated tablets in elderly patients there was observed (≥ 65 years) an increase compared to younger patients (<65 years), the incidence of headache (16.2% and 11.8%) and dizziness (3.7% and 0.7%). The overall incidence of adverse reactions (especially dizziness) was slightly higher in patients with hypertension in medical history.
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Levitra vs Viagra, Levitra vs Cialis
Levitra, Viagra and Cialis belong to phosphodiesterase type 5 drug family. They are virtually similar to one another, and yet there are some considerable differences which mainly set apart Levitra and Cialis. There is no conclusive answer which PDE5 inhibitor is best, since responsiveness and tolerance is strictly individual for patients. These are the main parameters that condition divergence between Levitra and Cialis and Levitra and Viagra:
Compatibility with food: Levitra can be taken with food, as well as Generic Viagra and Generic Cialis, but its effects will be the more delayed the higher the content of fat in meals – in contrast to Cialis whose absorption and onset of action are unaffected by fatty foods. Levitra and Viagra act similarly in relation to high-fat meals.
Compatibility with alcohol: Levitra is better not to be taken alongside with alcohol. Although taken in moderation alcohol will not considerably compromise the effects of vardenafil, it will certainly dial down the drug’s potential. Levitra and Cialis are contrasted in their relation with alcohol, since the latter is not considered an antagonist to Cialis. Levitra vs Viagra comparison in questions related to simultaneous alcohol consumption sees both medicines acting similarly.
Side event profile: Levitra compared to Viagra or Cialis produces the least number of side effects, and they are also least pronounced in their intensity. Therefore, patients displaying intolerance towards Viagra or Cialis most often find themselves tolerating the action of Levitra with none of the side events whatsoever.
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