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  • Clinical Trials or How Do We Get Effective Treatment Strategies

    Clinical trials are a special category of medical tests which are usually held to check the progress of some medical issues like treatment, implementation of new equipment, pill effectiveness etc. This procedure contributes greatly to the development of medical science in general.

    medical scienceThe capability of medical trials to provide the most accurate data should never be underestimated and very often the results become a decisive factor for the recognition of the statement. All clinical trials involve the participation of the human test subjects in small quantities. People are examined thoroughly in the very beginning and new methods of treatment are tested upon the members of the group together with possible side effects.

    The Essential Motives of the Clinical Trials

    The main goal of the clinical trials is to conduct the researches. There are general and specific clinical trials which are pursuing the same aim – acquiring the analyzed data.

    The standard guidelines of the process include:

    • The protection of trial participants;
    • The acquisition of precise data;
    • The creation of the new concept;
    • Organizing the process of investigation;
    • Exponential testing and progression;

    The clinical trials can have one of the following motives:

    • The necessity to evaluate the impact of the treatment for curing some sort of disease, state or apply a new therapy.
    • The development of new preventive measures against possible epidemics situations.
    • The study of some particular type of illness that is currently unknown for the modern medicine.
    • The investigation of newly developed health-issue identification technologies.
    • The study of the new care supportive manipulations.
    • The invention and testing of some procedures for the improvement of life among people with life-long chronical diseases.

    The results of the successful trial may discover a totally new strategy and some completely new impact on the improvement or worsening of the health state. The valuable information can be shared among the countries for the mutual medicine development.

    Phases of Clinical Trials

    The medical studies usually consist of several stages which are titled “phases”. They are identified by the Food and Drug Administration (FDA). Most of the procedure includes the following phases:

    0 Phase

    This phase starts the very creation of the formula and the test subject samples. In various cases it can be called “new drug” study. During this procedure the medication is created and the microdoses are given to the participants of text groups in order to gather pharmacokinetic and pharmacodynamics of the utilization.

    1st Phase

    This phase is usually titled “defining phase”. It has got no therapeutic or diagnostic goal. Most of the studies are simply gathering data. The information is used to figure out the mechanism of the medicine action and chemical processes which are connected with it. Several samples of various proportions are tested until the most successful formula is detected and only after that it can be used for therapeutic testing.

    2nd Phase

    This is a safety phase that involves more serious testing among the selected group of approximately 50 patients which are under constant surveillance. It is done in order to minimize the risks and verify all the major side effects which people will see on the leaflet in future when they buy the medicine in the shop.

    The third phase mainly involves proving of the effectiveness of medicine and the comparative analysis of the substance versus the placebo as it usually grants the best results. Here we observe rather large test groups of over several hundreds of participants where the toxicity level is also checked.

    4th Phase

    After passing all the investigation procedures the medicament reaches the final stage of confirmation. After all the major comparisons are finalized the title of drug is sent to the health organizations where the mass production is confirmed to put into action.

    Why are the clinical trials so valuable

    The medical science is constantly developing and with the help of this procedure the organization of health care can make totally new discoveries and implementation of them into everyday life.

    The researches open the mystery door and reveal the answers to the following three questions:

    1. If the new method is effective for people?
    2. How does the medicine influence on various groups of patients?
    3. What possible strategies can be developed based on the investigation?

    The clinical trials is a tiresome and time taking process that leads to progress and helps to deal with the most terrible health issues which were considered lethal several decades ago.

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